Foreign Policy ramifications will take a little longer to become apparent, but they will happen:
1) Israel, you're on your own. You can not count on any assistance from the US Government for at least the next 4 years. You won't get military assistance. If you are forced to defend yourself against your growing list of enemies in the region, we will not back you up. Though I have not heard any specifics, do not be surprised if military aid starts getting smaller.
However, watch for military aid to Egypt to continue. Watch for aid to your other enemies to begin, or increase.
Don't expect any concrete action from the United States in curbing Iran's nuclear endeavors - and if you decide to attack to defend yourselves, you are going to be on your own.
2) Watch for another round of unilateral disarmament from the United States. No treaty will be needed. Obama is simply going to continue the castration of our military, especially our nuclear deterrent forces. Remember, he has stated his goal is for our country to be free of nuclear weapons, and he's going to try to do it whether our 'friends' in Russia and China do or not.
3) Watch for the Obama Administration to move to accept UN oversight on many things, including gun control inside of the United States. Obama wants to show the world that we are subservient to the greater will of the UN - even though it is stuffed full of criminals, dictators, child molesters, thiefs, human traffickers, torturers, etc.
Watch for Obama to pledge hundreds of millions of dollars in taxpayer funds to renovate the decripit UN building in NY. The thing is falling apart, due to the fact that no other nation on Earth will put up any money to keep it up.
4) Hillary will sign some bullshit agreement with Iran, one that appears to curb their nuclear weapons program. It won't. There won't be any kind of verification. While she and Obama are crowing about their achievement in diplomacy, Iran will laugh their asses off and continue their work unimpeded.
If you will remember Hillary's bitch Bill, who came up with the same kind of agreement with North Korea in the 90s. What an achievement, we were told. North Korea will never have a nuclear weapon- honest, they promised us. Guess what ... a few years later, North Korea had the bomb, admited it, admited they lied about it, and thumbed their noses at us.